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Science Corner Index

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July14, 2008

I. Science and Service News Updates
II. Resources: Publications, Toolkits, Other Resources
III. Calls for Public Input
IV. Calls for Applications
V. Calendar of Events
VI. Funding Information
VII. Programmatic Funding Opportunities
VIII. Research Funding Opportunities (PAs and RFAs)

Print Version

Science and News Update

NIMH Schizophrenia Initiative Featured in Biological Psychiatry

An NIMH initiative to fill the gap between advances in basic cognitive neuroscience and practical clinical applications for patients with schizophrenia is the topic of the July 1, 2008 issue of Biological Psychiatry. It contains eight articles on the Cognitive Neuroscience Approaches to the Treatment of Impaired Cognition in Schizophrenia (CNTRICS) initiative, including a commentary, and descriptions of meetings related to the effort.

Science Update: http://www.nimh.nih.gov/science-news/2008/nimh-schizophrenia-initiative-featured-in-biological-psychiatry.shtml

HIV-associated Neurological Disease Prevalent in Asia-Pacific Region

A new study finds a significant rate of HIV-related neurological disease among HIV-positive populations living in the Asian-Pacific region. The study, funded by NIMH and the National Institute of Neurological Disorders and Stroke, was published July 1, 2008, in the journal Neurology.

Science Update: http://www.nimh.nih.gov/science-news/2008/hiv-associated-neurological-disease-prevalent-in-asia-pacific-region.shtml

NIMH: Couples-based Intervention May Limit HIV Transmission in African Countries

A shift to a couples-based intervention for married and cohabiting couples in urban Zambia and Rwanda could prevent up to 60 percent of new HIV infections that would otherwise occur, according to an NIMH-funded study published June 27, 2008, in The Lancet. The survey found that 45 to 75 percent of HIV-positive married individuals in Africa have HIV-negative spouses. Researchers estimate that 55 to 93 percent of new heterosexual HIV infections occur within marriages or cohabiting relationships.

Science Update: http://www.nimh.nih.gov/science-news/2008/couples-based-intervention-may-limit-hiv-transmission-in-african-countries.shtml

NIMH: Mice Expressing Human Genes Bred to Help Unravel Mental Disorders

New mouse strains engineered to express human genes related to mental disorders are being developed under a recently-launched grant program from NIMH’s Division of Neuroscience and Basic Behavioral Science. The new models are designed to help scientists understand the molecular workings of variations in genes that may predispose for – or even help protect against – illnesses like depression, bipolar disorder and schizophrenia. They will also explore how duplications or the differences in the amount of genetic material affect brain function, and how genes influence response to treatments.

Science Update: http://www.nimh.nih.gov/science-news/2008/mice-expressing-human-genes-bred-to-help-unravel-mental-disorders.shtml

NIMH: New Grant Supports Stem Cell-Derived Model of Autism-Related Illness

For the first time, researchers are developing a test tube model of Rett syndrome, a debilitating autism-like illness, in neurons derived from human embryonic stem cells. The study, recently funded by a grant from NIMH’s Division of Neuroscience and Basic Behavioral Science, addresses a crucial gap in understanding the workings of the rare autism spectrum disorder.

Science Update: http://www.nimh.nih.gov/science-news/2008/new-grant-supports-stem-cell-derived-model-of-autism-related-illness.shtml 

NIMH: Antipsychotic Medications May Ease Some Alzheimer’s Symptoms, Not Others

Antipsychotic medications may lessen symptoms like hostility and aggression in patients with Alzheimer’s disease, but do not appear to lessen other symptoms or improve quality of life, according to a recent analysis of data from the NIMH-funded Clinical Antipsychotic Trials of Intervention Effectiveness Alzheimer’s Disease (CATIE-AD) study. The analysis was published online ahead of print June 2, 2008, in the American Journal of Psychiatry.

Science Update: http://www.nimh.nih.gov/science-news/2008/antipsychotic-medications-may-ease-some-alzheimers-symptoms-not-others.shtml

NIMH: New Grant Aims to Overcome Obesity in People with Serious Mental Illness

A new grant funded by NIMH will test the effectiveness of a promising intervention designed to help people with serious mental illness who are overweight or obese lose weight and keep it off.

Science Update: http://www.nimh.nih.gov/science-news/2008/new-grant-aims-to-overcome-obesity-in-people-with-serious-mental-illness.shtml

NIMH: Anxious Youth Have Disturbed Brain Responses When Looking at Angry Faces

When looking at angry faces so quickly that they are hardly aware of seeing them, youth with generalized anxiety disorder (GAD) have unchecked activity in the brain’s fear center, say NIMH researchers. This disturbance is greater in those who are more severely anxious.

Science Update: http://www.nimh.nih.gov/science-news/2008/anxious-youth-have-disturbed-brain-responses-when-looking-at-angry-faces.shtml

NIDA: Broad Differences in Alcohol, Tobacco and Illegal Drug Use Across Countries

A survey conducted by the World Health Organization (WHO) research consortium found that the United States had among the highest lifetime rates of tobacco and alcohol use and led in the proportion of participants reporting cannabis (marijuana) or cocaine use at least once during their lifetime. The study, funded in part by the National Institute on Drug Abuse (NIDA) is published in the July 1, 2008 issue of the open access journal PLoS Medicine.

News Release:  http://www.nida.nih.gov/newsroom/08/NR6-30.html

New Subcommittee of HHS’ National Biodefense Science Board to Look at Mental Health Consequences of Disasters

The U.S. Department of Health and Human Services (HHS) announced that it is convening a group of national experts to develop recommendations on protecting, preserving and restoring individual and community mental health in catastrophic events.

News Release: http://www.hhs.gov/news/press/2008pres/06/20080626a.html

FDA Approves First Generic Risperidone to Treat Psychiatric Conditions

The U.S. Food and Drug Administration (FDA) approved the first generic versions of Risperdal (risperidone) tablets. Risperdal is an antipsychotic drug used for the treatment of schizophrenia, bipolar disorder, and other psychiatric conditions.

News Release: http://www.fda.gov/bbs/topics/NEWS/2008/NEW01855.html

FDA Issues an Information Sheet for Healthcare Professionals Sheet for Antipsychotics

The FDA is notifying healthcare professionals that conventional and atypical antipsychotics are associated with increased risk of mortality in elderly patients treated for dementia-related psychosis.

http://www.fda.gov/cder/drug/InfoSheets/HCP/antipsychotics_conventional.htm

Resources: Publications, Toolkits, Other Resources

Inside NIMH Newsletter: Summer 2008

http://www.nimh.nih.gov/research-funding/newsletter/2008-july-inside-nimh.html

NIH Research Matters: Success Quitting Smoking Based Partly on Genetics

Smokers' genetic make-up influences their chances for successful quitting. According to a new study, it may also help determine which treatment is most likely to help them quit.

http://www.nih.gov/news/research_matters/june2008/06232008quitting.htm

NIH News In Health: More than a Feeling How the Arts Affect Your Health

For thousands of years, people have searched for the meaning and beauty of life in music, painting, poetry and other arts. Now scientists are finding that the arts can benefit both your mental and physical health.

http://newsinhealth.nih.gov/2008/June/docs/01features_01.htm

NIDA InfoFacts - Treatment Approaches for Drug Addiction - Revision

This is a fact sheet covering research findings on effective treatment approaches for drug abuse and addiction.

http://www.nida.nih.gov/Infofacts/treatmeth.html

New SAMHSA Report Pinpoints Substance Use and Mental Health Problems in Individual Localities Throughout the Nation

Mental health and substance abuse problems affect every local community throughout America – but in unique, and sometimes surprising ways, according to a report by the Substance Abuse and Mental Health Services Administration (SAMHSA).  The report offers highly detailed analyses of the substance abuse and mental health problems occurring within these smaller geographical areas.

http://oas.samhsa.gov/substate2k8/toc.cfm

SAMHSA:  New Nationwide Report Estimates that 40 Percent of Underage Drinkers Received Free Alcohol from Adults Over 21

More than 40 percent of the nation’s estimated 10.8 million underage current drinkers (persons aged 12 to 20 who drank in the past 30 days) were provided free alcohol by adults 21 or older, according to a nationwide report by the Substance Abuse and Mental Health Services Administration.  The study also indicates that one in 16 underage drinkers (6.4 percent or 650,000) was given alcoholic beverages by their parents in the past month.

http://oas.samhsa.gov/underage2k8/toc.htm

AHRQ Podcast Features Patient Advisory Councils and Advice on Choosing a Health Plan

On Healthcare 411, Agency for Health Research and Quality Director Carolyn M. Clancy, M.D., offers consumers advice on how to select a health plan. This podcast also features the toolkit for creating community-based patient advisory councils and a News & Number story about online prescriptions

http://healthcare411.ahrq.gov/column.aspx?id=382

Living With Ma’i Suka: Individual, Familial, Cultural, and Environmental Stress Among Patients With Type 2 Diabetes Mellitus and Their Caregivers in American Samoa;

Preventing Chronic Disease, Volume 5: No. 3, July 2008

The U.S. territory of American Samoa has a disproportionate number of people with type 2 diabetes mellitus compared with neighboring Samoa and the U.S. mainland. The purpose of this research was to study perceptions of diabetes among people with type 2 diabetes in American Samoa in order to design culturally appropriate interventions to prevent and manage diabetes effectively.

http://www.cdc.gov/pcd/issues/2008/jul/07_0101.htm

GAO: Young Adults With Serious Mental Illness: Some States and Federal Agencies Are Taking Steps to Address Their Transition Challenges

Due to concerns about young adults with serious mental illness transitioning into adulthood, the Government Accountability Office was asked to provide information on (1) the number of these young adults and their demographic characteristics, (2) the challenges they face, (3) how selected states assist them, and (4) how the federal government supports states in serving these young adults and coordinates programs that can assist them.

http://www.gao.gov/docdblite/summary.php?rptno=GAO-08-678&accno=A82485

New PTSD Research Quarterly Newsletter (RQ)

The National Center produces the newsletter: PTSD Research Quarterly (RQ). Each RQ contains a review article written by guest experts on specific topics related to PTSD.

Spring 2008:  http://www.ncptsd.va.gov/ncmain/nc_archives/rsch_qtly/V19N2.pdf

Calls for Nominations
Calls for Public Input

Request for Information: Input on Public Mental Health Research Questions for NIMH’s interest in Suicide Prevention Efforts in Emergency Medicine Departments

The NIMH is seeking input on strategies to enhance suicide prevention efforts within emergency medicine department (ED) settings, where many individuals at high risk for suicide are seen.  Advice on identifying the most important mental health research questions is sought from the emergency medicine and clinical research communities, mental health professionals, suicide prevention and patient advocates, individuals who have survived a suicide attempt, private and public mental health service systems and providers, the pharmaceutical and biotechnology industry, and other interested groups or individuals.

Responses Due: July 25, 2008

http://grants.nih.gov/grants/guide/notice-files/NOT-MH-08-013.html

Request for Information: What Role Might the NIH (Neuroscience Blueprint) Play in Developing Neuroscience-Related Educational Materials for the K-12 Community?

The NIH Neuroscience Blueprint has released a Request for Information regarding neuroscience-related educational efforts for K-12 students. Biomedical science offers exciting opportunities and challenges to students. Discussions of the brain and nervous system can span many different courses, levels, and settings. The NIH Blueprint is interested in knowing what topics and curricula might be useful at the high-school level.

Responses Due: July 30, 2008

http://grants.nih.gov/grants/guide/notice-files/NOT-MH-08-012.html

ICDR Public Stakeholder Meeting

The Interagency Committee on Disability Research will be conducting public meetings for disability stakeholders on August 5 and August 13, 2008 from 9 am–12 pm and 1 pm–4 pm on both days in Arlington, Virginia with access by teleconference or Webcast. For more information on attending, providing written or oral testimony on disability research issues and concerns or watching the proceedings, go to: http://www.icdr.us/stakeholders/index.html

Deadline for Comments: July 21, 2008

Calls for Applications
Calendar of Events

The National Center for Trauma-Informed Care Learning Exchange

July 11-12, 2008, Washington, DC

The SAMHSA Center for Mental Health Services-funded National Center for Trauma-Informed Care will be hosting a two-day learning exchange and networking transformation forum to highlight useful and practical strategies for moving forward together with the implementation of trauma-informed care in organizations, programs, and services.

https://www.regonline.com/builder/site/Default.aspx?eventid=606344

2008 NIH Summer Institute on Health Services Research: Cross-Systems Research to Improve Health Outcomes

July 27 - August 1, 2008, Bethesda, Maryland

The 2008 NIH Summer Institute will address essential conceptual, methodological, and practical issues involved in planning and carrying out cross-systems health services research. The Institute is intended for investigators who have completed their doctorate and who plan to develop entry-level (e.g.: R03, R21, or R34) NIH grant applications for research in this area. Faculty will include established investigators from social work and other fields. The goal is for every participant to develop a draft grant proposal by the end of the training that will eventually lead to a grant submission to the relevant NIH institute.

http://conferences.thehillgroup.com/obssr/summerinstitute2008/index.html

Paving the Road Home: The National Behavioral Conference on Returning Veterans and Their Families

August 11, 2008, Bethesda, Maryland

Sponsored by SAMHSA, Department of Defense, and Department of Veteran Affairs, this national conference will help Federal, State, and local partners improve and enhance mental health and substance abuse services for returning veterans and their families. The conference will facilitate nationwide sharing of information on mental health and substance abuse services and supports across multiple health care delivery systems. Attendees will be provided science-based information to assist veterans and their families in building resiliency and preventing and/or treating complex conditions, including mental disorders (e.g., TBI, PTSD) substance use disorders, suicide, homelessness, domestic violence, and co-occurring disorders.

http://samhsa.gov/vets/NationalConference_Vets.pdf

AHRQ's 2008 Annual Conference: Promoting Quality — Partnering for Change

September 7-10, 2008, Bethesda, Maryland

The Agency for Healthcare Research Quality’s (AHRQ) 2008 Annual Conference will The conference will again bring together the best of the Agency's research and provide examples of how that research is being implemented at all levels in health care delivery. http://www.ahrq.gov/about/ahrqconf08.htm

3rd National Conference on Women, Addiction and Recovery

September 15-17, 2008, Tampa, Florida

SAMHSA’s 3rd National Conference on Women, Addiction and Recovery brings together the leaders, directors and other stakeholders in women’s services to hear current research, discuss implementation and promote effective leadership to professionals and stakeholders to assist women with substance use disorders and their families.

http://www.samhsa.gov/spotlights/WomenConference.aspx

The 13th Annual Conference on Advancing School Mental Health

September 25-27, 2008, Phoenix, Arizona

Sponsored by the Health Resources and Services Administration’s Center for School Mental Health and the IDEA Partnership, this year’s conference theme is “School Mental Health for All Students: Building a Shared Agenda for Youth, Families, Schools, and Communities.”

http://csmh.umaryland.edu/conf_meet/AnnualConference/index.html

The 14th NIMH Biennial Research Conference on the Economics of Mental Health: Toward Building a High Performance Mental Health System

September 25–26, 2008, Washington, DC

This biennial economics conference is an integral part of the dissemination and research portfolio development activities of the Division of Services and Intervention Research of NIMH. These scientific conferences are convened exclusively for presentation and discussion of original, rigorous and innovative technical research papers in mental health economics.

http://www.nimh.nih.gov/research-funding/scientific-meetings/announcements/2008/the-14th-nimh-biennial-research-conference-on-the-economics-of-mental-health-toward-building-a-high-performance-mental-health-sy.shtml

National Conference on Child Abuse and Neglect Call for Abstracts

March 30 - April 4, 2009, Atlanta, GA

The 17th National Conference on Child Abuse and Neglect, sponsored by the U.S. Department of Health and Human Services Children's Bureau Office on Child Abuse and Neglect (OCAN). The theme for the 2009 conference, "Focusing on the Future: Strengthening Families and Communities," emphasizes the need for every child to enjoy a healthy family life in a nurturing community.  The deadline for submission is August 15, 2008.

http://cbexpress.acf.hhs.gov/articles.cfm?issue_id=2008-07&article_id=1626

Funding Information
Programmatic Funding Opportunities
Research Funding Opportunities (PAs and RFAs)

Selected NIH Program Announcements (PAs)

[Full listing of NIH PAs at http://grants2.nih.gov/grants/guide/pa-files/index.html]

 

            Silvio O. Conte Centers for Basic and Translational Mental Health Research (P50)

http://grants.nih.gov/grants/guide/pa-files/PAR-08-194.html

 

Novel Lentiviral Models of HIV Neuropathogenesis

http://grants.nih.gov/grants/guide/pa-files/PAS-08-178.html (R01)

http://grants.nih.gov/grants/guide/pa-files/PAS-08-179.html (R21)

 

Medications Development for Polydrug Addiction Treatment

http://grants.nih.gov/grants/guide/pa-files/PAS-08-187.html (R21)

http://grants.nih.gov/grants/guide/pa-files/PAS-08-186.html (R01)

Selected NIH Request for Applications (RFAs)

[Full listing of NIH RFAs at http://grants2.nih.gov/grants/guide/rfa-files/index.html]

 

Criminal Justice Drug Abuse Treatment Studies 2 (CJ-DATS 2) (U01)

http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-09-006.html

 

Improving Effectiveness of Smoking Cessation Interventions and Programs in Low Income Adult Populations

http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-08-022.html (R01)

http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-08-023.html (R21)

 

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